Imre Mager
Senior Post Doctoral Researcher/Team Leader
Dr Imre Mager is studying the biology and pathophysiology of extracellular vesicles with an aim to identify new therapeutic pathways in disease (e.g. cancer, neurodegenerative and neuromuscular diseases), and an aim to bioengineer extracellular vesicles for the delivery of biotherapeutic drugs.
Recent publications
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An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.
Feneberg E. et al, (2020), Neurobiol Dis, 144
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A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA.
de Jong OG. et al, (2020), Nat Commun, 11
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CSF extracellular vesicle proteomics demonstrates altered protein homeostasis in amyotrophic lateral sclerosis.
Thompson AG. et al, (2020), Clin Proteomics, 17
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Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics.
Coenen-Stass AML. et al, (2019), RNA Biol, 16, 696 - 706
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UFLC-Derived CSF Extracellular Vesicle Origin and Proteome.
Thompson AG. et al, (2018), Proteomics, 18