Senior Post Doctoral Researcher/Team Leader
Tom Roberts is a senior research scientist in the Department of Paediatrics where he leads a team with the overall theme of ‘RNA medicine’. His research interests include neuromuscular disorders, RNA biology, extracellular nucleic acids, biomarkers, epigenetics, and gene/oligonucleotide therapies. Tom studied at the University of Oxford for both his undergraduate degree in Molecular and Cellular Biochemistry and doctoral degree in Physiology, Anatomy and Genetics (thesis title: Duchenne Muscular Dystrophy: RNA-based therapeutics and microRNA biology). He subsequently moved to San Diego, California where he undertook postdoctoral training positions at the Scripps Research Institute, Department of Molecular and Experimental Medicine (laboratory of Professors Kevin Morris and Marc Weinberg) and Sanford Burnham Prebys Medical Discovery Institute, Development, Aging and Regeneration Program (laboratory of Professor Lorenzo Puri). He later returned to the University of Oxford, Department of Paediatrics where he re-joined the Wood group
EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method
Hanson B. et al, (2023), Molecular Therapy - Nucleic Acids, 33, 511 - 528
Therapeutic approaches for Duchenne muscular dystrophy.
Roberts TC. et al, (2023), Nat Rev Drug Discov
An extracellular vesicle delivery platform based on the PTTG1IP protein
Perez CM. et al, (2023)
Investigating Eukaryotic Elongation Factor 2 Kinase/Eukaryotic Translation Elongation Factor 2 Pathway Regulation and Its Role in Protein Synthesis Impairment during Disuse-Induced Skeletal Muscle Atrophy.
Vilchinskaya N. et al, (2023), Am J Pathol, 193, 813 - 828
Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery
Liang X. et al, (2023)