Thomas Roberts
Senior Post Doctoral Researcher/Team Leader
Tom Roberts is a senior research scientist in the Department of Paediatrics where he leads a team with the overall theme of ‘RNA medicine’. His research interests include neuromuscular disorders, RNA biology, extracellular nucleic acids, biomarkers, epigenetics, and gene/oligonucleotide therapies. Tom studied at the University of Oxford for both his undergraduate degree in Molecular and Cellular Biochemistry and doctoral degree in Physiology, Anatomy and Genetics (thesis title: Duchenne Muscular Dystrophy: RNA-based therapeutics and microRNA biology). He subsequently moved to San Diego, California where he undertook postdoctoral training positions at the Scripps Research Institute, Department of Molecular and Experimental Medicine (laboratory of Professors Kevin Morris and Marc Weinberg) and Sanford Burnham Prebys Medical Discovery Institute, Development, Aging and Regeneration Program (laboratory of Professor Lorenzo Puri). He later returned to the University of Oxford, Department of Paediatrics where he re-joined the Wood group
Recent publications
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uORF-targeting steric block antisense oligonucleotides do not reproducibly increase RNASEH1 expression
Ahlskog N. et al, (2025), Molecular Therapy - Nucleic Acids, 36, 102406 - 102406
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An extracellular vesicle delivery platform based on the PTTG1IP protein
Martin Perez C. et al, (2024), Extracellular Vesicle, 4, 100054 - 100054
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uORF-targeting steric block antisense oligonucleotides do not reproducibly activate RNASEH1 expression
Ahlskog N. et al, (2024)
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Long-term dystrophin restoration supports development of splice correction therapy for DMD patients with exon 2 duplications
Roberts TC., (2023), Molecular Therapy Methods and Clinical Development, 31
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EV-mediated promotion of myogenic differentiation is dependent on dose, collection medium, and isolation method
Hanson B. et al, (2023), Molecular Therapy - Nucleic Acids, 33, 511 - 528