Carlo Rinaldi
ASSOCIATE PROFESSOR Wellcome Trust Clinician Scientist , Honorary Consultant Neurologist
My overall research interest is the application of genetic knowledge to benefit human health. This goal is pursued through three strategic aims: (1) identification of genes associated with neurological diseases, (2) advancement of the current understanding of the molecular mechanisms of pathogenesis in these diseases, and (3) development of effective treatments for hereditary neurological diseases.
Recent publications
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A modular RNA delivery system comprising spherical nucleic acids built on endosome-escaping polymeric nanoparticles
Journal article
Garcia-Guerra A. et al, (2023), Nanoscale Advances
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AR cooperates with SMAD4 to maintain skeletal muscle homeostasis.
Journal article
Forouhan M. et al, (2022), Acta Neuropathol, 143, 713 - 731
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MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties.
Journal article
Chopra N. et al, (2021), Mol Psychiatry, 26, 5636 - 5657
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Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity.
Journal article
Lim WF. et al, (2021), Sci Adv, 7
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Targeting the 5' untranslated region of SMN2 as a therapeutic strategy for spinal muscular atrophy.
Journal article
Winkelsas AM. et al, (2021), Mol Ther Nucleic Acids, 23, 731 - 742